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fkbp1b

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Official Full Name
FK506 binding protein 1B, 12.6 kDa
Background
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
Synonyms
FKBP1B; FK506 binding protein 1B, 12.6 kDa; FK506 binding protein 1B (12.6 kD) , FKBP1L; peptidyl-prolyl cis-trans isomerase FKBP1B; FKBP9; FKBP12.6; OTK4; PPIase; 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; Calstabin 2; FK506 binding protein 1 like; FK506 binding protein 12.6; FK506 binding protein 1B 12.6 kDa; FK506 binding protein 1B; FK506-binding protein 1B; FKB1B_HUMAN; FKBP 12.6; FKBP 1B; FKBP 1L; FKBP 9; FKBP-12.6; FKBP-1B; FKBP1L; h FKBP 12; h-FKBP-12; Immunophilin FKBP12.6; OTK 4; Peptidyl prolyl cis trans isomerase 1B; Peptidyl prolyl cis trans isomerase; PKBP 1L; PKBP1L; PPIase 1B; PPIase FKBP1B; Rotamase 1B; Rotamase; OTTHUMP00000116040; OTTHUMP00000116041; FK506-binding protein 12.6; 12.6 kDa FK506-binding; zgc:73381; si:dkeyp-115a10.1

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