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fhl1

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Official Full Name
four and a half LIM domains 1
Background
This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
Synonyms
FHL1; four and a half LIM domains 1; four and a half LIM domains protein 1; bA535K18.1; FHL1B; FLH1A; KYO T; LIM protein SLIMMER; MGC111107; SLIM1; XMPMA; FHL 1; FHL 1B; FHL-1; FHL1 protein; FHL1_HUMAN; FHL1A; Four and a half Lin11 Isl 1 and Mec 3 domains 1; RAM14-1; RBP associated molecule 14-1; Skeletal muscle LIM protein 1; Skeletal muscle LIM-protein 1; SLIM 1; SLIM; SLIM-1; SLIMMER; OTTHUMP00000024097; OTTHUMP00000024098; OTTHUMP00000024099; OTTHUMP00000024100; OTTHUMP00000024101; OTTHUMP00000024102; OTTHUMP00000024103; OTTHUMP00000024104; OTTHUMP00000024106; OTTHUMP00000024107; skeleta; KYOT; skeletal muscle LIM-protein1; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; KYOT, SLIM, FHL-1, FHL1A, FHL1B, FLH1A, SLIM1, XMPMA, SLIM-1, SLIMMER

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