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fbxo3

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Official Full Name
F-box protein 3
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants diverging at the 3 end.
Synonyms
FBXO3; F-box protein 3; F box only protein 3; F-box only protein 3; FBA; FBX3; F box protein 3; F box protein FBX3; F-box protein FBX3; DKFZp564B092; zgc:112485

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