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fblim1

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Official Full Name
filamin binding LIM protein 1
Background
This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
FBLIM1; filamin binding LIM protein 1; filamin-binding LIM protein 1; CAL; FBLP 1; migfilin; FBLP1; Mitogen inducible 2 interacting protein; OTTHUMP00000003118; OTTHUMP00000003119; OTTHUMP00000003120; 2410043F08Rik; CSX associated LIM; DKFZp434G171; FBLI1_HUMAN; FBLIM 1; FBLP-1; Gt10; MGC105665; MIG2 interacting protein; MIG2-interacting protein; Mitogen-inducible 2-interacting protein; OTTMUSP00000011062; OTTMUSP00000011063; RP11-169K16.5; RP23-291H3.1; CSX-associated LIM; OTTHUMP00000221650; filamin-binding LIM protein-1; mitogen-inducible 2 interacting protein; mitogen-inducible 2-intera; CAL, FBLP1, FBLP-1, RP11-169K16.5; wu:fa28a10; zgc:154176; fa28a10

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