Official Full Name
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
FARP1; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); FERM, RhoGEF and pleckstrin domain-containing protein 1; CDEP; MGC87400; PLEKHC2; PPP1R75; protein phosphatase 1; regulatory subunit 75; Chondrocyte derived ezrin like protein; FERMRhoGEF and pleckstrin domain containing protein 1; FERM RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); PH domain-containing family C member 2; chondrocyte-derived ezrin-like protein; protein phosphatase 1, regulatory subunit 75; pleckstrin homology domain-containing family C member 2