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exosc1

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Official Full Name
exosome component 1
Background
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
Synonyms
EXOSC1; exosome component 1; exosome complex component CSL4; CGI 108; CSL4; CSL4 exosomal core protein homolog (yeast); Csl4p; hCsl4p; p13; SKI4; Ski4p; RP11-452K12.9; 3-5 exoribonuclease CSL4 homolog; exosomal core protein CSL4; CSL4 exosomal core protein homolog; homolog of yeast exosomal core protein CSL4; CGI-108

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