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ercc6

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Official Full Name
excision repair cross-complementation group 6
Background
This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B.
Synonyms
ERCC6; excision repair cross-complementing rodent repair deficiency, complementation group 6; CSB; CKN2; COFS; ARMD5; COFS1; RAD26; DNA excision repair protein ERCC-6; Rad26 homolog; Cockayne syndrome B protein; ATP-dependent helicase ERCC6; cockayne syndrome protein CSB; Cockayne syndrome group B protein; OTTHUMP00000019581; EC 3.6.4.-; EC 3.6.1

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