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elavl1

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Official Full Name
ELAV like RNA binding protein 1
Background
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3 untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]
Synonyms
ELAVL1; ELAV like RNA binding protein 1; HUR; Hua; MelG; ELAV1; ELAV-like protein 1; Hu antigen R; hu-antigen R; embryonic lethal, abnormal vision, drosophila, homolog-like 1; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R); embryonic lethal; abnormal vision; drosophila; homolog like 1; RNA-binding protein HuA; elra; zHuA; fa25f08; fb59a02; fc60g02; wu:fa25f08; wu:fb59a02; wu:fc60g02; etID309757.2; elav-related A; embryonic lethal, abnormal vision-related A; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1

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