This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
ECI2; enoyl-CoA delta isomerase 2; PECI, peroxisomal D3,D2 enoyl CoA isomerase; enoyl-CoA delta isomerase 2, mitochondrial; Hepatocellular carcinoma associated antigen 88; ACBD2; acyl Coenzyme A binding domain containing 2; DRS1; HCA88; DBI-related prote; PECI; DRS-1; dJ1013A10.3; DBI-related protein 1; dodecenoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; renal carcinoma antigen NY-REN-1; delta(3),delta(2)-enoyl-CoA isomerase; peroxisomal D3,D2-enoyl-CoA isomerase; peroxisomal 3,2-trans-enoyl-CoA isomerase; acyl-Coenzyme A binding domain containing 2; diazepam-binding inhibitor-related protein 1; hepatocellular carcinoma-associated antigen 88; EC 126.96.36.199