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ebi3

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Official Full Name
Epstein-Barr virus induced 3
Background
This gene was identified by its induced expression in B lymphocytes in response Epstein-Barr virus infection. It encodes a secreted glycoprotein belonging to the hematopoietin receptor family, and heterodimerizes with a 28 kDa protein to form interleukin 27 (IL-27). IL-27 regulates T cell and inflammatory responses, in part by activating the Jak/STAT pathway of CD4+ T cells.
Synonyms
EBI3; Epstein-Barr virus induced gene 3; interleukin-27 subunit beta; IL-27B; IL-27 subunit beta; epstein-Barr virus-induced gene 3 protein homolog; EBI-3; IL-27; Epstein-Barr virus induced 3; IL27 subunit; IL35 subunit; cytokine receptor; EBV-induced gene 3 protein; epstein-Barr virus-induced gene 3 protein; IL27B; il-27rb; si:dkey-97a13.4; Il27rbeta; interleukin 27 receptor beta

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