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ebf3

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Official Full Name
early B-cell factor 3
Background
This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins;are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors.;The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and;apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including;glioblastoma multiforme and gastric carcinoma.
Synonyms
EBF3; early B-cell factor 3; COE3; DKFZp667B0210

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