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drosha

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Official Full Name
drosha, ribonuclease type III
Background
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM, Mar 2008]
Synonyms
DROSHA; drosha, ribonuclease type III; RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976; ribonuclease 3; p241; RNase III; protein Drosha; nuclear RNase III Drosha; putative ribonuclease III; ribonuclease III, nuclear; ribonuclease type III, nuclear; drosha, double-stranded RNA-specific endoribonuclease; putative protein p241 which interacts with transcription factor Sp1

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