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dram1

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Official Full Name
DNA-damage regulated autophagy modulator 1
Background
This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Synonyms
DRAM1; DNA-damage regulated autophagy modulator 1; DNA damage-regulated autophagy modulator protein 1; damage regulated autophagy modulator; DRAM; FLJ11259; damage-regulated autophagy modulator; zgc:101811

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