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dolk

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Official Full Name
dolichol kinase
Background
The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.
Synonyms
DOLK; dolichol kinase; TMEM15, transmembrane protein 15; DK1; dolichol kinase 1; KIAA1094; CDG1M; DK; SEC59; SEC59, YEAST, HOMOLOG OF; TMEM15; Transmembrane protein 15; SEC59 homolog; zgc:162284

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