DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which interacts specifically with hepatitis C virus core protein resulting a change in intracellular location. This gene has a homolog located in the nonrecombining region of the Y chromosome. The protein sequence is 91% identical between this gene and the Y-linked homolog.
ATP dependent RNA helicase DDX3X; DEAD box protein 3 X-chromosomal; DEAD box X isoform; Fibroblast Growth Factor Inducible 14; Fin14; Helicase like protein 2; HLP2; DDX3X; DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked; DDX3, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 3; ATP-dependent RNA helicase DDX3X; DBX; DDX14; CAP-Rf; DEAD/H box-3; DEAD box, X isoform; helicase-like protein 2; DEAD box protein 3, X-chromosomal; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3; DDX3