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ddc

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Official Full Name
dopa decarboxylase (aromatic L-amino acid decarboxylase)
Background
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine,;L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic;L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that;leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding;different isoforms have been identified for this gene.
Synonyms
DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); aromatic-L-amino-acid decarboxylase; AADC; dopa decarboxylase; zgc:65801; zgc:76929; wu:fa56d05; wu:fd59h03; wu:fk20h01; aromatic amino acid decarboxylase

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