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cxcl16

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Official Full Name
chemokine (C-X-C motif) ligand 16
Background
Chemokine (C-X-C motif) ligand 16 (CXCL16), also known as SR-PSOX, is a transmembrane protein that facilitates uptake of low density lipoproteins by macrophages, resulting in foam cell formation. CXCL16 is found in liver tissue2 and influences the uptake, subcellular localization, and cytokine profile induced by D oligonucleotides. 3 CXCL16 may play a pro- inflammatory role in Inflammatory Bowel Disease (IBD), particularly Crohns disease.
Synonyms
chemokine (C-X-C motif) ligand 16; SRPSOX; CXCLG16; SR-PSOX; CXCL16; CXC chemokine ligand 16; Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; Small-inducible cytokine B16; Transmembrane chemokine CXCL16; C-X-C motif chemokine 16; SR PSOX

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