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ctdp1

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Official Full Name
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
Background
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Synonyms
CTDP1; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1; FCP1; CCFDN; RNA polymerase II subunit A C-terminal domain phosphatase; serine phosphatase FCP1a; TFIIF-associating CTD phosphatase 1; CTD of POLR2A, phosphatase of, subunit 1; transcription factor IIF-associating CTD phosphatase 1

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