Official Full Name
COP9 signalosome subunit 3
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene.
COPS3; COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis); COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 3; COP9 signalosome complex subunit 3; CSN3; SGN3; signalosome subunit 3; COP9 complex subunit 3; JAB1-containing signalosome subunit 3; COP9 signalosome subunit 3; COP9 constitutive photomorphogenic homolog subunit 3; zgc:55643; zgc:77615; wu:fc32a02; wu:fk59f01; zgc:111903