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colec11

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Official Full Name
collectin sub-family member 11
Background
This gene encodes a member of the collectin family of C-type lectins that possess collagen-like sequences and;carbohydrate recognition domains. Collectins are secreted proteins that play important roles in the innate immune;system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. The encoded;protein binds to multiple sugars with a preference for fucose and mannose. Mutations in this gene are a cause of 3MC;syndrome-2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
COLEC11; collectin sub-family member 11; MGC3279; 3MC2; CLK1; CL-K1-I; CL-K1-II; CL-K1-IIa; CL-K1-IIb; collectin-11; CL-2; cCL-2; collectin 2; collectin-2; wu:fb82e09; zgc:103572

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