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cog2

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Official Full Name
component of oligomeric golgi complex 2
Background
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes. Mutations of this gene are associated with abnormal glycosylation within the Golgi apparatus. Alternative splicing results in multiple transcript variants.
Synonyms
COG2; component of oligomeric golgi complex 2; LDLC, low density lipoprotein receptor defect C complementing; conserved oligomeric Golgi complex subunit 2; Brefeldin A sensitive peripheral Golgi protein; COG 2; COG complex subunit 2; Conserved oligomeric Golgi complex component 2; LDLC; Low density lipoprotein receptor defect C complementing protein; Transcript ch4822; OTTHUMP00000035875; OTTHUMP00000035876; conserved oligomeric Golgi complex protein 2; brefeldin A-sensitive, peripheral Golgi protein; low density lipoprotein receptor defect C complementing; l; low density lipoprotein receptor defect C-complementing protein; zC8A9.2; zgc:56436

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