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cnga1

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Official Full Name
cyclic nucleotide gated channel alpha 1
Background
The protein encoded by this gene is involved in phototransduction. Along with another protein, the encoded protein forms a cGMP-gated cation channel in the plasma membrane, allowing depolarization of rod photoreceptors. This represents the last step in the phototransduction pathway. Defects in this gene are a cause of retinitis pigmentosa autosomal recessive (ARRP) disease. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
CNGA1; cyclic nucleotide gated channel alpha 1; CNCG, CNCG1; cGMP-gated cation channel alpha-1; CNG1; RCNC1; RCNCa; photoreceptor; cGMP gated cation channel alpha 1; CNCG; CNCG1; CNG 1; CNG channel alpha 1; CNG channel alpha-1; CNG-1; CNGA1_HUMAN; Cyclic nucleotide gated cation channel 1; Cyclic nucleotide gated channel photoreceptor; Cyclic nucleotide-gated cation channel 1; Cyclic nucleotide-gated channel alpha-1; Cyclic nucleotide-gated channel; Interleukin 1 homologue; OTTHUMP00000218675; OTTHUMP00000223313; OTTHUMP00000223314; RCNCalpha; Rod photoreceptor cGMP gated channel subunit alpha; Rod photoreceptor cGMP-gated channel subunit alpha; RP49; interleukin-1 homologue; cyclic nucleotide-gated channel, photoreceptor; rod photoreceptor cGMP-gated channel subuni; cyclic nucleotide-gated channel rod photoreceptor subunit alpha; CNG3; CNG-3; CNG channel 3; alpha subunit of rod photoreceptor CNG-channel

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