This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene.
CLIP3; CAP-GLY domain containing linker protein 3; CAP-Gly domain-containing linker protein 3; CLIP 170 related; CLIPR 59; restin like 1; RSNL1; CAP GLY domain containing linker protein 3; CLIP 170 related 59 kDa protein; CLIP-170-related 59 kDa protein; CLIP3_HUMAN; CLIPR-59; CLIPR59; Cytoplasmic linker protein 170 related 59 kDa protein; Cytoplasmic linker protein 170-related 59 kDa protein; restin-like 1; FLJ33413; DKFZp586N1922