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clec7a

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Official Full Name
C-type lectin domain family 7, member A
Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded;glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a;cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition;receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this;way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms,;have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the;natural killer gene complex region.
Synonyms
CLEC7A; C-type lectin domain family 7, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12 , CLECSF12; C-type lectin domain family 7 member A; dectin 1; hDectin 1; Beta GR; BGR; C type calcium dependent carbohydrate recognition domain lectin superfamily member 12; C type lectin domain family 7 member a; CLEC7A protein; Clecsf12; DECTIN 1 receptor; Dectin1; Dendritic cell associated C type lectin 1; Lectin like receptor 1; Putative transmembrane protein dectin 1; dectin-1; OTTHUMP00000164964; OTTHUMP00000164965; OTTHUMP00000164966; OTTHUMP00000233744; OTTHUMP00000233745; OTTHUMP00000233746; OTTHUMP00000233748; OTTHUMP00000233749; beta-glucan receptor; lectin-like receptor 1; DC-associat; CANDF4; DC-associated C-type lectin 1; C-type lectin superfamily member 12; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12

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