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chrnb1

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Official Full Name
cholinergic receptor, nicotinic, beta 1 (muscle)
Background
The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.
Synonyms
CHRNB1; cholinergic receptor, nicotinic, beta 1 (muscle); acetylcholine receptor subunit beta; Acetylcholine receptor protein beta chain precursor; ACHB_HUMAN; ACHRB; Cholinergic receptor nicotinic beta polypeptide 1 (muscle); Chrnb 1; CHRNB; CMS1D; CMS2A; Nicotinic acetylcholine receptor beta subunit precursor; SCCMS; cholinergic receptor, nicotinic, beta polypeptide 1 (muscle); cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) , CHRNB; acetylcholine receptor; nicotinic; beta 1 (muscle); acetylcholine receptor, nicotinic, beta 1 (muscle); FLJ57107; AChR beta1b; acetylcholine receptor subunit beta 1; nicotinic acetylcholine receptor subunit beta 1b

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