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chmp5

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Official Full Name
charged multivesicular body protein 5
Background
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006
Synonyms
CHMP5; charged multivesicular body protein 5; C9orf83, chromatin modifying protein 5 , chromosome 9 open reading frame 83 , SNF7DC2; CGI 34; HSPC177; Vps60; C9orf83; CHMP 5; Chromatin modifying protein 5; Chromosome 9 open reading frame 83; HGNC:26942; hVps60; PNAS 2; SNF7 domain containing protein 2; SNF7DC2; Vacuolar protein sorting 60; SNF7 domain containing 2; chromatin-modifying protein 5; SNF7 domain-containing protein 2; apoptosis-related protein PNAS-2; vacuolar protein sorting-associated protein 60; CGI-34; PNAS-2; Vps60, CGI-34, PNAS-2, C9orf83, HSPC177, SNF7DC2

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