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chit1

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Official Full Name
chitinase 1 (chitotriosidase)
Background
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
Synonyms
CHIT1; chitinase 1 (chitotriosidase); chitotriosidase-1; CHI3; CHIT; CHIT1_HUMAN; Chitinase 1; Chitinase-1; Chitotriosidase; EC 3.2.1.14; FLJ00314; MGC125322; Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase; OTTHUMP00000039092; OTTHUMP00000217083; OTTHUMP00000217084; OTTHUMP00000217085; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase; CHITD

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