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celf1

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Official Full Name
CUGBP, Elav-like family member 1
Background
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms
CELF1; CUGBP, Elav-like family member 1; CUG triplet repeat, RNA binding protein 1 , CUG triplet repeat, RNA binding protein 1 , CUGBP1; CUGBP Elav-like family member 1; bruno like 2; BRUNOL2; CUG RNA binding protein; CUG BP; CUGBP; EDEN BP; embryo deadenylation element binding protein; hNab50; NAB50; NAPOR; nuclear polyadenylated RNA binding protein; 50 kD; 50 kDa Nuclear polyadenylated RNA binding protein; Deadenylation factor CUG BP; RNA binding protein BRUNOL 2; 50 kDa nuclear polyadenylated RNA-binding protein; bruno like protein 2; Bruno-like protein 2; BRUNOL 2; CELF 1; CELF-1; CELF1 CUGBP, Elav like family member 1; CELF1_HUMAN; CUG BP and ETR 3 like factor 1; CUG BP1; CUG triplet repeat RNA binding protein 1; CUG triplet repeat RNA-binding protein 1; CUG-BP- and ETR-3-like factor 1; CUG-BP1; CUGBP 1; CUGBP and ETR3 like factor 1; CUGBP Elav like family member 1; CUGBP1; Cytidine Uridine Guanosine Binding Protein 1; Deadenylation factor CUG-BP; Deadenylation factor CUGBP; EDEN BP homolog; EDEN-BP homolog; embryo deadenylation element binding protein homolog; Embryo deadenylation element-binding protein homolog; hNab 50; NAB 50; Nuclear polyadenylated RNA binding protein 50 kD; RNA binding protein BRUNOL2; RNA-binding protein BRUNOL-2; bruno-like 2; CUG RNA-binding protein; CUG; CUG-BP; EDEN-BP; CUG triplet repeat, RNA bindi; brul; cb920; Bruno-like; EDEN-BP/Bruno-like protein; CUG triplet repeat

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