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cdt1

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Official Full Name
chromatin licensing and DNA replication factor 1
Background
The protein encoded by this gene is involved in the formation of the pre-replication complex that is necessary for DNA replication. The encoded protein can bind geminin, which prevents replication and may function to prevent this protein from initiating replication at inappropriate origins. Phosphorylation of this protein by cyclin A-dependent kinases results in degradation of the protein. [provided by RefSeq, Mar 2011]
Synonyms
CDT1; chromatin licensing and DNA replication factor 1; DUP; RIS2; DNA replication factor Cdt1; Double parked, Drosophila, homolog of

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