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cdrt1

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Official Full Name
CMT1A duplicated region transcript 1
Background
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Synonyms
HREP; SM25H2; C170RF1; C17ORF1; FBXW10B; C17ORF1A; FBXW10P1; FBXW10

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