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cdh7

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Official Full Name
cadherin 7, type 2
Background
This gene is a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures. Alternative splicing in the 5 UTR of this gene yields variant transcripts encoding the same protein.
Synonyms
CDH7; cadherin 7, type 2; cadherin-7; CDH7L1; cadherin-7 type II

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