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ccng2

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Official Full Name
cyclin G2
Background
The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle.
Synonyms
CCNG2; cyclin G2; cyclin-G2; CCNG 2; CCNG2 protein; CyclinG2; cb438; zgc:77125; wu:fa08f07; wu:fk28c06; wu:fk91a03

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