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ccndbp1

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Official Full Name
cyclin D-type binding-protein 1
Background
This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009]
Synonyms
CCNDBP1; cyclin D-type binding-protein 1; HHM; DIP1; GCIP; cyclin-D1-binding protein 1; human homolog of Maid; D-type cyclin-interacting protein 1; grap2 and cyclin-D-interacting protein; D type cyclin interacting protein 1; grap2 cyclin interacting protein; HHM Protein; MAID protein

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