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cbx1

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Official Full Name
chromobox homolog 1
Background
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The;protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal;chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain;(CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone;proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression.;Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding;the same protein, have been identified.
Synonyms
CBX1; chromobox homolog 1; chromobox homolog 1 (Drosophila HP1 beta); chromobox protein homolog 1; CBX; HP1 beta homolog (Drosophila ); HP1 BETA; HP1Hs beta; M31; MOD1; HP1 beta homolog; modifier 1 protein; heterochromatin protein 1-beta; heterochromatin protein p25 beta; heterochromatin protein 1 homolog beta; chromobox homolog 1 (HP1 beta homolog Drosophila ); p25beta; HP1-BETA; HP1Hsbeta; HP1Hs-beta

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