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cbfa2t2

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Official Full Name
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Background
In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5-region of the RUNX1 (AML1) gene fused to the 3
Synonyms
CBFA2T2; core-binding factor, runt domain, alpha subunit 2; translocated to, 2; protein CBFA2T2; MTGR1; ZMYND3; MTG8-like protein; MTG8-related protein 1; ETO homolog on chromosome 20; ETO homologous on chromosome 20; myeloid translocation-related protein; myeloid translocation-related protein 1; myeloid translocation gene-related protein 1; EHT; p85; DKFZp313F2116

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