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c1qtnf1

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Official Full Name
C1q and tumor necrosis factor related protein 1
Background
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Synonyms
C1QTNF1; C1q and tumor necrosis factor related protein 1; GIP; CTRP1; ZSIG37; complement C1q tumor necrosis factor-related protein 1; G protein coupled receptor interacting protein; g protein-coupled receptor-interacting protein; FLJ90694; zgc:113062

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