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brwd3

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Official Full Name
bromodomain and WD repeat domain containing 3
Background
The protein encoded by this gene contains a bromodomain and several WD repeats. It is thought to have a chromatin-modifying function, and may thus play a role in transcription. Mutations in this gene cause mental retardation X-linked type 93, which is also referred to as mental retardation X-linked with macrocephaly. This gene is also associated with translocations in patients with B-cell chronic lymphocytic leukemia.
Synonyms
BRWD3; bromodomain and WD repeat domain containing 3; bromodomain and WD repeat-containing protein 3; FLJ38568; MRX93; novel WD repeat domain protein; bromo domain-containing protein disrupted in leukemia; BRODL; FLJ33254

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