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birc2

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Official Full Name
baculoviral IAP repeat containing 2
Background
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Synonyms
BIRC2; baculoviral IAP repeat containing 2; API1; MIHB; HIAP2; RNF48; cIAP1; Hiap-2; c-IAP1; baculoviral IAP repeat-containing protein 2; IAP-2; IAP homolog B; apoptosis inhibitor 1; RING finger protein 48; inhibitor of apoptosis protein 2; baculoviral IAP repeat-containing 2; NFR2-TRAF signalling complex protein; TNFR2-TRAF-signaling complex protein 2; API1, baculoviral IAP repeat containing 2; c IAP1; hiap 2; NFR2 TRAF signalling complex protein; ITA; IAP1; inhibitor of apoptosis protein; IAP homolog; inhibitor of apoptosis 1; inhibitor of T-cell apoptosis protein; birc3; baculoviral IAP repeat-containing 3; bZ1P14.6.2 (baculoviral IAP repeat-containing 3 )

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