Creative biogene
SHARE THIS
facebook twitterlinkedingoogle plusStumbleUpon blog


  Order Info:   order info
Products
CBpromise

24x7 CUSTOMER SERVICE

CONTACT US TO ORDER

;

bin1

Bookmark and Share
Official Full Name
bridging integrator 1
Background
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a;MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system;may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin.;Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and;activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in;cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different;isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Synonyms
BIN1; bridging integrator 1; AMPHL; myc box-dependent-interacting protein 1; AMPH2; amphiphysin II; SH3P9; amphiphysin-like protein; box dependant MYC interacting protein 1; box-dependent myc-interacting protein 1; MGC10367; DKFZp547F068

CONTACT CREATIVE BIOGENE

45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-626-9181
Fax: 1-631-614-7828
Email: info@creative-biogene.com

Europe
Tel: 44-207-097-1828

Terms & Conditions | Privacy Policy | Sitemap | FAQ | © 2010-2017 Creative Biogene. All Rights Reserved.
-->