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bdh1

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Official Full Name
3-hydroxybutyrate dehydrogenase, type 1
Background
This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described.
Synonyms
BDH1; 3-hydroxybutyrate dehydrogenase, type 1; 3 hydroxybutyrate dehydrogenase (heart, mitochondrial) , BDH; D-beta-hydroxybutyrate dehydrogenase, mitochondrial; SDR9C1; short chain dehydrogenase/reductase family 9C; member 1; 3 hydroxybutyrate dehydrogenase (heart, mitochondrial); BDH; D beta hydroxybutyrate dehydrogenase, mitochondrial; OTTHUMP00000208056; OTTHUMP00000208057; OTTHUMP00000208058; OTTHUMP00000208059; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase; short chain dehydrogenase/reductase family 9C, member 1; MGC2723; MGC4347; MGC9788; BDH, SDR9C1; zgc:163053

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