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b3gnt3

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Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
Background
This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking.
Synonyms
B3GNT3; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3; TMEM3; B3GN T3; B3GNT 3; beta 1; 3 N acetylglucosaminyltransferase bGnT 3; beta3Gn T3; HP10328; putative type II membrane protein; transmembrane protein 3; B3GAL T8; B3GALT8; Beta 1,3 galactosyltransferase 8; Beta 3 Gal T8; Beta3Gal T8; Beta3GalT8; BGnT 3; BGnT3; Core 1 extending beta 1,3 N acetylglucosaminyltransferase; Core1 beta3GlcNAcT; UDP Gal:beta GlcNAc beta 1,3 galactosyltransferase 8; UDP GlcNAc:betaGal beta 1,3 N acetylglucosaminyltransferase 3; beta-3-Gx-T8; beta-1,3-Gn-T3; beta-1,3-GalTase 8; core1-beta3GlcNAcT; beta-1,3-N-acetylglucosaminyltransferase bGnT-3; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8; core 1 extending beta-1,3-N-acetylglucosaminyltransferase; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8; B3GN-T3; B3GNT-3; B3GAL-T8; beta3Gn-T3; TMEM3, B3GN-T3, B3GNT-3, HP10328, B3GAL-T8, beta3Gn-T3; wu:fk30b12; zgc:171538; beta-3-galactosyltransferase-like

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