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atl1

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Official Full Name
atlastin GTPase 1
Background
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms
ATL1; atlastin GTPase 1; spastic paraplegia 3A (autosomal dominant) , SPG3, SPG3A; atlastin-1; AD FSP; atlastin; FSP1; Atlastin1; Brain specific GTP binding protein; GBP3; SPG 3A; SPG3; GBP-3; hGBP3; GTP-binding protein 3; guanylate-binding protein 3; spastic paraplegia 3 protein A; brain-specific GTP-binding protein; guanine nucleotide-binding protein 3; HSN1D; SPG3A; AD-FSP; fj46c01; wu:fj46c01

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