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appl2

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Official Full Name
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
Background
APPL2 is an isoform of APPL1 with 54% identity in their protein sequences. APPL2 has a role in cell proliferation and embryonic development. Recently, it was shown that APPL2 regulates FSH signaling and acts as a negative regulator in adiponectin signalin
Synonyms
APPL2; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2; DCC-interacting protein 13-beta; DIP13B; FLJ10659; DIP13 beta; adapter protein containing PH domain, PTB domain and leucine zipper motif 2

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