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amn

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Official Full Name
amnion associated transmembrane protein
Background
The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.
Synonyms
AMN; amnionless homolog (mouse); protein amnionless; visceral endoderm-specific type 1 transmembrane protein; PRO1028; amnion associated transmembrane protein; amnionless homolog; amnionless protein

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