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alg2

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Official Full Name
ALG2, alpha-1,3/1,6-mannosyltransferase
Background
This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants.
Synonyms
ALG2; asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); asparagine linked glycosylation 2 homolog (yeast, alpha 1,3 mannosyltransferase); alpha-1,3/1,6-mannosyltransferase ALG2; CDGIi; FLJ14511; hALPG2; NET38; OTTHUMP00000123474; 3-mannosyltransferase ALG2; ALG2_HUMAN; Alpha 1,3 mannosyltransferase ALG2; Alpha-1; Asparagine linked glycosylation protein 2; Asparagine-linked glycosylation protein 2 homolog; GDP Man:Man(1)GlcNAc(2) PP dolichol mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase; OTTHUMP00000021785; RP11-13B9.1; homolog of yeast ALG2; alpha-1,3-mannosyltransferase ALG2; GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase; asparagine-linked glycosylation 2 homolog (yeast, alpha-1,3-mannosyltransferase); asparagine-linked glycosylation 2 homolog (S. cerevisiae, alpha-1,3-mannosyltransferase); CDGIi, NET38, hALPG2; asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase); im:7145131

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