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alg10

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Official Full Name
ALG10, alpha-1,2-glucosyltransferase
Background
This gene encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc(2)-PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel.
Synonyms
ALG10; asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); asparagine linked glycosylation 10, alpha 1,2 glucosyltransferase homolog (yeast); dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; derepression of ITR1 expression 2 homolog (S. cerevisiae); DIE2; FLJ14751; ALG 10; ALG10A; Alpha 1,2 glucosyltransferase ALG10 A; Alpha 2 glucosyltransferase ALG10 A; Alpha2 glucosyltransferase; Asparagine linked glycosylation 10 alpha 1,2 glucosyltransferase homolog (S. pombe); Asparagine linked glycosylation 10 alpha 1,2 glucosyltransferase homolog (yeast); Asparagine linked glycosylation 10 homolog (yeast, alpha 1,2 glucosyltransferase); Asparagine linked glycosylation protein 10 homolog A; Derepression of ITR1 expression 2 homolog; KCR1; Potassium channel regulator 1; alpha2-glucosyltransferase; alpha-2-glucosyltransferase ALG10-A; alpha-1,2-glucosyltransferase ALG10-A; asparagine-linked glycosylation protein 10 homolog A; asparagine-linked glycosylation 10 homolog (yeast, alpha-1,2-glucosyltransferase); ALG10B; modifier of the HERG potassium channel; asparagine-linked glycosy

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