Official Full Name
A kinase (PRKA) anchor protein 3
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.
AKAP3; A kinase (PRKA) anchor protein 3; A-kinase anchor protein 3; AKAP110; cancer/testis antigen 82; CT82; Fibrous Sheath Protein of 95 kDa; FSP95; SOB1; AKAP-3; AKAP 110; fibrousheathin 1; fibrousheathin I; fibrousheathin-1; fibrous sheath protein, 95k; fibrous sheath protein, 95kDa; sperm oocyte-binding protein 1; A-kinase anchor protein 110 kDa; A-kinase anchor protein, 110kDa; protein kinase A anchoring protein 3; protein kinase A-anchoring protein 3; PRKA3