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abcc4

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Official Full Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
ABCC4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; MRP4; MOATB; MOAT-B; EST170205; multidrug resistance-associated protein 4; MRP/cMOAT-related ABC transporter; multispecific organic anion transporter B; ATP-binding cassette sub-family C member 4; multi-specific organic anion transporter B; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); bA464I2.1 (ATP binding cassette; sub family C (CFTR/MRP); member 4); MOAT B; multidrug resistance associated protein 4; MRP4, MOATB, MOAT-B, EST170205; MRP; cb1019; dZ52I16.4; si:dz52i16.4; si:dz202l16.5; si:busm1-52i16.4; multidrug resistance-associated protein member 4

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