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ZYX


Official Full Name
zyxin
Organism
Homo sapiens
Gene ID
7791
Background
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
Synonyms
ESP-2; HED-2

Cat.No. Product Name Price
SHL163962 shRNA set against Mouse Zyx(NM_011777.2) Inquiry
SHH456204 shRNA set against Human ZYX (NM_003461.4) Inquiry
SHH456208 shRNA set against Mouse ZYX (NM_011777.2) Inquiry
SHH456212 shRNA set against Rat ZYX (NM_053761.1) Inquiry
SHL163846 shRNA set against Human ZYX(NM_001010972.1) Inquiry
SHW000147 shRNA set against Chicken ZYX (NM_001004386) Inquiry
SHW011954 shRNA set against Danio rerio ZYX (NM_001109824) Inquiry
Cat.No. Product Name Price
CDCB161622 Chicken ZYX ORF Clone (NM_001004386) Inquiry
CDCB188546 Rabbit ZYX ORF clone (XM_008258091.1) Inquiry
CDCR285704 Human ZYX ORF Clone(NM_003461.4) Inquiry
CDFH022222 Human ZYX cDNA Clone(NM_001010972.1) Inquiry
CDFH022223 Human ZYX cDNA Clone(NM_003461.4) Inquiry
CDFL015680 Mouse Zyx cDNA Clone(NM_011777.2) Inquiry
CDFR013443 Rat Zyx cDNA Clone(NM_053761.1) Inquiry
MiUTR1H-11777 ZYX miRNA 3'UTR clone Inquiry
MiUTR1M-13230 ZYX miRNA 3'UTR clone Inquiry
MiUTR3H-04591 ZYX miRNA 3'UTR clone Inquiry
SKO0945 ZYX Validated sgRNA vector Inquiry
CDCB173429 Danio rerio ZYX ORF Clone (NM_001109824) Inquiry
CDCR251288 Mouse Zyx ORF Clone(NM_011777.2) Inquiry
CDCR340934 Human ZYX ORF Clone(NM_001010972.1) Inquiry
CDCR380541 Rat Zyx ORF Clone(NM_053761.1) Inquiry
CDCS406452 Human ZYX ORF Clone (BC008743) Inquiry
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