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ZMIZ1


Official Full Name
zinc finger MIZ-type containing 1
Organism
Homo sapiens
Gene ID
57178
Background
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Synonyms
MIZ; RAI17; ZIMP10; NEDDFSA; TRAFIP10

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